Rosuvastatin zinc salt
AssigneeEgis Gyogyszergyar Nyilvanosan Mukodo Reszvenytarsasag
InventorsPal Vago, Gyula Simig, Gyoergy Clementis, Peter Toempe, Sandorne Tapai
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Abstract
The present invention is related to rosuvastatin zinc salt of the Formula (I), process for preparation thereof and medicinal products containing said salt. Rosuvastatin zinc salt according to the present invention is prepared by reacting rosuvastatin with a zinc alcoholate, zinc enolate or an inorganic or organic zinc salt and isolating the thus obtained rosuvastatin zinc salt (2:1).
Claims3
Medicinal products containing (+)-7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulphonyl-amino)pyrimidin-5-yl]-(3R,5S)-dihydroxy-(E)-6-heptenecarboxylic acid zinc salt (2:1) of the formula (I) in admixture with one or more pharmaceutically acceptable vehicle or auxiliary agent.
(+)-7-[4-(4-fluorophenyl)-6-isopropyl-2 -(N-methyl-N-methylsulphonyl-amino)pyrimidin-5-yl]-(3R,5S)-dihydroxy-(E)-6-heptenecarboxylic acid zinc salt (2:1) of the formula (I)
- or a hydrate thereof.
Dependencies are inferred from the claim text.