Crystalline lopinavir/surfactant adducts
AssigneeAbbVie Inc.
InventorsYuchuan Gong, Geoff G. Zhang, Matthias Degenhardt, Markus Maegerlein
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Abstract
This invention relates to novel crystalline lopinavir/surfactant adducts, methods for their preparation, therapeutic uses of those crystalline lopinavir/surfactant adducts, and pharmaceutical compositions containing them or made from them.
Claims9
A single crystal of crystalline lopinavir/surfactant adduct characterized by an XRPD pattern having peaks at 4.8, 7.3, 8.8, 9.7, 10.3, 12.2, 12.8, 14.7, 16.4, 17.6, 18.6, 20.0, 21.9, 22.5, and 23.0°2θ±0.2°2θ.
A single crystal of crystalline lopinavir/surfactant adduct characterized by an IR spectrum having a peak at 1730 cm−1.
A single crystal of crystalline lopinavir/surfactant adduct characterized by a Raman spectrum having peaks at 3398, 3066, 3042, 2925, 2968, 1660, 1643, 1606, 1585, 1446, 1381, 1346, 1267, 1238, 1209, 1033, 1004, 958, 883, 791, 754, 697, 622, and 532 cm−1±1 cm−1.
Dependencies are inferred from the claim text.