Soft rock inhibitors

A compound of Formula I or a stereoisomer, tautomer, racemic, or salt, thereof,

• Wherein,
• X is hydrogen or halogen;
• Y is —NH—C(═O)— or —C(═O)—NH—;
• Z1, Z2, and Z3 are each independently selected from the group consisting of C, N, O, and S;
• R1 is selected from the group consisting of hydrogen, C1-20alkyl, and C3-15cycloalkyl;
• R2 is selected from the group consisting of hydrogen, C1-20alkyl, halogen and C1-20alkoxy;
• R3 is selected from the group consisting of C1-20alkyl, C3-20alkenyl, C3-20alkynyl, C3-15cycloalkyl, aryl, heteroaryl, and C3-19heterocyclyl;
• wherein said C1-20alkyl, C3-20alkenyl, C3-20alkynyl, C3-15cycloalkyl, aryl, heteroaryl, and C3-19heterocyclyl is optionally substituted with one or more substituents selected from the group consisting of halo, hydroxyl, oxo, carbonyl, amino, amido, cyano, aryl, heteroaryl, C3-15cycloalkyl, C3-19heterocyclyl, C1-20alkylamino, di(C1-20alkyl)amino, C1-20alkoxy, halo-C1-20alkoxy, halo-C1-20alkyl, thiol, C1-20alkylthio, carboxylic acid, acylamino, C1-20alkyl esters, carbamate, thioamido, urea, and sulfonamido;
• and
• n is 0 or 1.