Integrated process of distillation with side reactors for synthesis of organic acid esters

An integrated process for synthesizing organic acid esters comprising:

• (a) establishing an alcohol and organic acid composition;
• (b) reacting said alcohol and organic acid composition in a pre-reactor to form at least one ester;
• (c) separating water from said alcohol and organic acid composition to form a separated reaction product mixture;
• (d) introducing said separated reaction product mixture into an upper zone of a distillation column, said distillation column having a plurality of distillation zones, said distillation zones arranged in upper and bottom distillation zones, wherein the step of introducing the separated reaction product mixture into said upper distillation zone of a distillation column is followed by the steps of:
• (a1) drawing a liquid side stream from a predetermined zone of said distillation column which is sequentially lower than said upper distillation zone into at least one first side reactor;
• (b1) passing an effluent stream from said first side reactor to a heat exchanger;
• (c1) drawing a vapor stream from said heat exchanger for combining with said overhead vapor stream of said distillation column;
• and
• (d1) drawing a liquid stream from said heat exchanger for re-introduction into said distillation column;
• (e) drawing a column overhead vapor stream off of said separated reaction product mixture from an upper distillation zone;
• (f) passing said reaction product mixture through a plurality of distillation zones in the distillation column for distilling said organic esters from said introduced separated reaction product mixture liquid;
• and
• (g) removing enriched organic ester from a bottom distillation zone of said distillation column.