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US 9,174,917 B2Granted
Bexarotene analogs
AssigneeArizona Board of Regents on behalf of Arizona State University
InventorsCarl E. Wagner, Peter W. Jurutka, Pamela A. Marshall, Arjan van der Vaart
Life of this patent
Estimating the term…
Abstract
The present invention relates to analogs of bexarotene and methods of use thereof.
Claims10
A compound having the structural formula:
- wherein R1 is hydrogen, halogen, or CO2H;
- R2 is halogen, or CO2H;
- R3 is CO2H;
- and
- R4 is hydrogen, halogen, or CO2H;
- or a pharmaceutically acceptable salt thereof.
3 more elements
A compound having the structural formula:
- or a pharmaceutically acceptable salt thereof wherein R2 and R1 are defined as:
- Compound #
- R1
- R2
- 10
- Cl
- H
- 11
- Br
- H
- 12
- I
- H
- 10a
- H
- Cl
- 11a
- H
- Br
- 12a
- H
- I
- 10b
- Cl
- Cl
- 11b
- Br
- Br
- 12b
- I
- I.
28 more elements
Dependencies are inferred from the claim text.