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US 9,173,979 B2Granted
Bioabsorbable polymeric compositions, processing methods, and medical devices therefrom
AssigneeEthicon, Inc.
InventorsBrian M. Kelly, Dennis D. Jamiolkowski, Christopher DeFelice
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Abstract
Novel bioabsorbable polymeric blends are disclosed. The blends have a first component that is a polylactide polymer or a copolymer of lactide and glycolide and a second component that is poly(p-dioxanone) polymer. The novel polymeric blends provide medical devices having dimensional stability. Also disclosed are novel bioabsorbable medical devices made from these novel polymer blends, as well as novel methods of manufacture.
Claims33
A method of manufacturing a bioabsorbable medical device, comprising the steps of:
- processing a bioabsorbable polymer blend comprising 78 weight percent to 82 weight percent of a first bioabsorbable polymer and 18 weight percent to 22 weight percent of a second bioabsorbable polymer, the first bioabsorbable polymer comprising a lactide-rich polymer comprising 95 mol percent to 70 mol percent polymerized lactide and 5 mol percent to 30 mol percent polymerized glycolide, and the second bioabsorbable polymer comprising poly(p-dioxanone),
- wherein the maximum weight percent of poly(p-dioxanone) in the polymer blend is 22 weight percent and the minimum weight percent of poly(p-dioxanone) in the polymer blend depends upon the molar amount of polymerized lactide in the lactide-rich polymer and is calculated by the expression:
- Minimum Weight Percent Poly(p-dioxanone)=(215.6212/Mol Percent Polymerized Lactide)27027
- and forming a bioabsorbable medical device from the polymer blend, wherein the polymer blend provides dimensional stability to the formed device.
1 more element
Dependencies are inferred from the claim text.