Methods and compositions for promoting wound healing
OwnerRichard E. Wooley, Branson W. Ritchie +3inventors
InventorsRichard E. Wooley, Branson W. Ritchie, Douglas T. Kemp, Anthony C. Capomacchia, Victoria V. Burnley
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Abstract
The present invention provides methods and compositions that use the combination of Tris and EDTA to inhibit the growth of microorganisms at the site of a wound or burn, and/or to promote the healing of a wound or burn, and/or to reduce the sensation of pain at the site of a wound or burn. The amount of Tris and EDTA applied to a wound or burn can be selected to achieve one or more of the foregoing effects.
Claims10
A method of promoting healing of a burn on a mammalian, bird, or reptile body in need thereof, the method comprising applying to said burn an amount of a composition consisting of Tris, EDTA, and dissolved silver in a pharmaceutically acceptable carrier selected from the group consisting of water, saline, physiological saline, an ointment, a cream, an oil-water emulsion, and a gel, wherein the silver, Tris, and EDTA are in amounts sufficient to promote healing of a burn on a mammalian, bird, or reptile body, the composition consisting of a pH of from 6.0 to 9.0, and optionally, a detergent, a vitamin, an anti-inflammatory agent, lecithin, glycerin, methyl paraben, aloe vera, polypropylene glycol ethoxylate, and/or poloxamer 407, effective to promote healing therefor.
A method of promoting healing of a wound in, or on, a living mammalian, bird, or reptile body in need thereof, the method comprising applying to or in said wound an amount of a composition consisting of Tris, EDTA, and dissolved silver in a pharmaceutically acceptable carrier selected from the group consisting of water, saline, physiological saline, an ointment, a cream, an oil-water emulsion, and a gel, wherein the silver, Tris, and EDTA are in amounts sufficient to promote healing of a burn on a mammalian, bird, or reptile body, the composition consisting of a pH of from 6.0 to 9.0, and optionally, a detergent, a vitamin, an anti-inflammatory agent, lecithin, glycerin, methyl paraben, aloe vera, polypropylene glycol ethoxylate, and/or poloxamer 407, effective to promote healing therefor.
A method of treating a burn in a human subject in need thereof comprising administering to the human subject a therapeutically effective amount of a composition consisting of Tris, EDTA, and dissolved silver in a pharmaceutically acceptable carrier selected from the group consisting of water, saline, physiological saline, an ointment, a cream, an oil-water emulsion, and a gel, wherein the silver, Tris, and EDTA are in amounts sufficient to promote healing of a burn on a mammalian, bird, or reptile body, the composition having consisting of a pH of from 6.0 to 9.0, and optionally, a detergent, a vitamin, an anti-inflammatory agent, lecithin, glycerin, methyl paraben, aloe vera, polypropylene glycol ethoxylate, and/or poloxamer 407, effective to promote healing therefor.
A method of treating a wound in a human subject in need thereof comprising administering to the human subject a therapeutically effective amount of a composition consisting of Tris, EDTA, and dissolved silver in a pharmaceutically acceptable carrier selected from the group consisting of water, saline, physiological saline, an ointment, a cream, an oil-water emulsion, and a gel, wherein the silver, Tris, and EDTA are in amounts sufficient to promote healing of a burn on a mammalian, bird, or reptile body, the composition consisting of a pH of from 6.0 to 9.0, and optionally, a detergent, a vitamin, an anti-inflammatory agent, lecithin, glycerin, methyl paraben, aloe vera, polypropylene glycol ethoxylate, and/or poloxamer 407, effective to promote healing therefor.
Dependencies are inferred from the claim text.