Simple adhesive coacervates and methods of making and using thereof
AssigneeUniversity of Utah Research Foundation
InventorRussell J. Stewart
Life of this patent
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Abstract
Described herein is the synthesis of adhesive from simple adhesive coacervates and their uses thereof. The adhesives are produced by (a) preparing a solution comprising (1) a polyelectrolyte, wherein the polyelectrolyte comprises a polyanion or polycation but not a combination thereof, the polyeletrolyte comprises at least one crosslinking group, and (2) a sufficient amount of a complimentary counterion to produce a simple adhesive coacervate; and (b) crosslinking the simple adhesive coacervate to produce the adhesive. The adhesives have numerous medical and non-medical applications.
Claims27
An adhesive produced by the process comprising
- (a) preparing a simple adhesive coacervate comprising (1) a polyelectrolyte, wherein the polyelectrolyte comprises a polyanion or polycation but not a combination thereof, the polyeletrolyte comprises at least one crosslinking group, and wherein a photoinitiator and optionally a co-initiator are covalently attached to the polycation and/or polyanion, (2) a sufficient amount of a complimentary counterion to produce a simple adhesive coacervate, and (3) a polymerizable monomer, a water-insoluble filler, or a combination thereof;
- and
- (b) crosslinking the simple adhesive coacervate to produce the adhesive.
A method for modifying the one or more surface properties of a substrate, the method comprising applying to the substrate surface a simple adhesive coacervate prepared by combining (1) a polyelectrolyte, wherein the polyelectrolyte comprises a polyanion or polycation but not a combination thereof, the polyeletrolyte comprises at least one crosslinking group, and wherein a photoinitiator and optionally a co-initiator are covalently attached to the polycation and/or polyanion (2) a sufficient amount of a complimentary counterion to produce a simple adhesive coacervate, and (3) a polymerizable monomer, a water-insoluble filler, or a combination thereof, wherein a photoinitiator and optionally a co-initiator are covalently attached to the polycation and/or polyanion.
Dependencies are inferred from the claim text.