Ferrimannitol-ovalbumin tablet composition
AssigneeTedee Meiji Farma, S.A.
InventorsAna Isabel Torres-Suarez, Daniel Filipe Tavares Da Silva Fernandes, Maria Esther Gil Alegre
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Abstract
The invention refers to an oral pharmaceutical tableted dosage form which comprises a mixture of: a) granules comprising ferrimannitol-ovalbumin (FMOA) and at least an intragranular pharmaceutical acceptable excipient including a binder; and b) extragranular pharmaceutical excipients including a filler and a binder; which may be obtained by wet-granulation and compression.
Claims26
An orodispersible pharmaceutical tableted dosage form which comprises a mixture of:
- a) granules produced by wet granulation of ferrimannitol-ovalbumin (FMOA), and at least an intragranular pharmaceutically acceptable excipient including an intragranular binder selected from the group consisting of starches, microcrystalline cellulose, povidone, hydroxypropyl cellulose, hydroxyethyl cellulose, hydroxypropylmethyl cellulose and mixtures thereof;
- and
- b) extragranular pharmaceutical excipients including an extragranular filler and an extragranular binder,
- wherein the extragranular binder is present in an amount of from about 2% to 8% by weight.
An oral pharmaceutical tabletted dosage form prepared by compression with a tableting punch, which comprises a mixture of:
- a) granules produced by wet granulation of ferrimannitol-ovalbumin (FMOA), and at least an intragranular pharmaceutically acceptable excipient including an intragranular binder;
- and
- b) extragranular pharmaceutical excipients including an extragranular filler and an extragranular binder,
- said extragranular binder being selected from the group consisting of starches, microcrysralline cellulose, povidone, hydroxypropyl cellulose, hydroxyethyl cellulose, hydroxypropylmethyl cellulose and mixtures thereof;
- wherein said extragranular binder is present in an amount effective to prevent sticking to said tabletting punch.
An oral pharmaceutical tabletted dosage form prepared by compression with a tableting punch, which comprises a mixture of:
- a) granules comprising ferrimannitol-ovalbumin (FMOA), and at least an intragranular pharmaceutically acceptable excipient including an intragranular binder;
- and
- b) extragranular pharmaceutical excipients including an extragranular filler and an extragranular binder,
- said extragranular binder and said intragranular binder each being selected from the group consisting of povidone, hydroxypropyl cellulose, hydroxyethyl cellulose, hydroxypropylmethyl cellulose, and mixtures thereof;
- wherein said extragranular binder is present in an amount effective to prevent sticking to said tabletting punch.
Dependencies are inferred from the claim text.