Nutritional supplement and use thereof
AssigneeZyCal Bioceuticals Healthcare Company, Inc.
InventorJames Scaffidi
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Abstract
Nutritional supplements and methods for maintaining and/or improving the condition of bones or cartilage in a mammal, particularly a human. One such supplement comprises demineralized bone matrix (DBM) wherein the DBM comprises a bone growth improving amount of at least one osteoinductive growth factor. A preferred supplement composition further comprises at least one vitamin, such as vitamin E. One method comprises orally administering to the mammal on a periodic basis a supplement comprising DBM. In a preferred method the DBM composition is periodically administered and there is a further periodic administration of a therapeutically effective amount of a calcium-containing composition; the calcium-containing composition is administered temporally spaced apart from said DBM composition for maximum effectiveness.
Claims20
A method for maintaining or improving the condition of bone or a joint in a mammal comprising orally administering to said mammal on a periodic basis a composition comprising demineralized bone matrix (DBM) derived from a source of bone comprising native bone-active substances
- wherein said native bone-active substances in said source of bone comprise native Bone Morphogenic Proteins, (BMPs) and native Transforming Growth Factors-β, (TGF-β),
- said DBM comprising at least one native bone-active substance selected from the group consisting of native Bone Morphogenic Proteins, (BMPs) and native Transforming Growth Factors β, (TGF-β),
- wherein said DBM, BMPs, and TGF-β are in therapeutically effective amounts to manage a bone or joint condition or bone or joint health in said mammal.
Dependencies are inferred from the claim text.