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US 9,173,850 B2Granted
4-methylpyrazole formulations
AssigneeRaptor Pharmaceuticals Inc.
InventorsThomas E. Daley, Kathy Powell, Olga Jarzebinski
Life of this patent
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Abstract
Provided herein are 4-methylpyrazole (4-MP) formulations, stable under storage conditions of up to about 55° C.
Claims20
A solid formulation comprising:
- (a) 4-methylpyrazole, or a physiologically acceptable salt form thereof;
- and
- (b) an excipient, wherein the excipient is a polyethylene glycol having a total weight average molecular weight of from 5000 to 10,000 Da;
- wherein the formulation is in a solid form at temperatures of from at least 25° C. to up to about 40° C.
1 more element
A hard gelatin capsule encapsulating:
- (a) 4-methylpyrazole, or a physiologically acceptable salt form thereof;
- and
- (b) an excipient, wherein the excipient is a polyethylene glycol having a total weight average molecular weight of from 5000 to 10,000 Da;
- wherein the capsule retains physical integrity when stored for 8 months or more at room temperature and at relative humidities of up to about 60%±5%.
1 more element
Dependencies are inferred from the claim text.