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US 9,173,844 B2Granted
Pharmaceutical solid preparation
AssigneeOtsuka Pharmaceutical Co., Ltd.
InventorKai Suzuki
Life of this patent
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Abstract
An object of the present invention is to provide a gradual disintegration-type, sustained-release pharmaceutical solid preparation whose pharmacologically active substance release behavior is controlled. The solid pharmaceutical preparation of the present invention is a matrix-type preparation containing: (a) a pharmacologically active substance; (b) calcium polycarbophil; and (c) a specific sugar and/or sugar alcohol.
Claims18
A gradual disintegration-type and matrix-type pharmaceutical solid preparation comprising:
- (a) tolvaptan;
- (b) calcium polycarbophil;
- and
- (c) a sugar and/or sugar alcohol, the (c) sugar and/or sugar alcohol being at least one member selected from the group consisting of trehalose, lactitol, maltose, maltitol, sucrose, sorbitol, xylitol, erythritol, mannitol, lactose, and isomaltooligosaccharide.
1 more element
Dependencies are inferred from the claim text.