Method and apparatus for personalized physiologic parameters

A method of predicting an impending patient cardiac event, the method comprising:

• receiving from an adherent device impedance data measured with respect to a patient;
• receiving from an input mechanism patient descriptive data indicating at least one characteristic of the patient;
• establishing, via a processor, at least one patient-specific value for the patient based at least in part on the impedance data, wherein establishing at least one patient-specific value comprises processing the impedance data to establish a baseline impedance specific to the patient and a baseline breath parameter specific to the patient and computing a predicted impedance specific to the patient based on the patient descriptive data;
• making ongoing measurements of the impedance via the adherent device and computing ongoing measurements of the breath parameter via the processor;
• computing via the processor an impedance index indicative of a change in the impedance relative to the baseline impedance over time;
• computing via the processor a breath index indicative of a change in the breath parameter relative to the baseline breath parameter over time;
• computing via the processor a predicted impedance index indicative of a change in the impedance relative to the predicted impedance over time;
• and
• generating based at least in part on comparisons of the impedance index, the breath index, and the predicted impedance index with respective preselected thresholds performed by the processor, a patient event prediction output predictive of the impending patient cardiac event.