US 9,169,212 B2Granted

Azepane derivatives and methods of treating hepatitis B infections

AssigneeNovira Therapeutics, Inc.

InventorsGeorge D. Hartman, Scott Kuduk

Life of this patent

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Abstract

Provided herein are compounds useful for the treatment of HBV infection in a subject in need thereof, pharmaceutical compositions thereof, and methods of inhibiting, suppressing, or preventing HBV infection in the subject.

Claims20

Dependent claims

A compound, or a pharmaceutically acceptable salt thereof, selected from:

Dependencies are inferred from the claim text.

Facts

Application: 14/511,964Filed 10 Oct 2014 · us provisional application
Priority: 16 Jan 2014
Published: US 2015/0197493 A116 Jul 2015
Granted: 27 Oct 2015
Term ends: Not estimatedThe source records don’t support an estimate.

Classification25 codes

C07D 223/08
With hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals,…:…
A61K 31/439
Having six-membered rings with one nitrogen as the only ring hetero atom: the ring forming part of a bridged ring system, e.g. quinuclidine
A61K 31/52
Ortho- or peri-condensed with heterocyclic rings: purines, e.g. adenine
A61K 31/5377
1,4-Oxazines, e.g. morpholine: not condensed and containing further heterocyclic rings, e.g. timolol

Family

Application61/928,130Us provisional application · filed 16 Jan 2014
US 2015/0197493 A1Pre-grant publication · published 16 Jul 2015
US 9,169,212 B2This patent

From the US filing history. Foreign family members aren’t listed.

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