Chamber for sealed junction device and aseptic transfer device

A first chamber (1) suitable for being combined with a second chamber (2) to form a sealed junction device, the first chamber (1) comprising:

• A structure that includes a closed wall (3) that borders an inside space (1a),
• At least one opening (4) in the wall (3), the opening bordered by an annular first flange (5) whose outside surface (5a) is configured to ensure a hermetically-sealed flattening onto itself of an outside surface (9a) of a second complementary flange (9) that is part of the second chamber (2),
• A holding means, configured to hold the first flange (5) and the second flange (9) when they are flattened against one another by their outside surfaces (5a and 9a),
• A first door (6) supported by the structure by a movable or deformable carrying means (11a), the first door comprising a first panel (6v) configured to be moved to be either in a closed state where it works with the first flange (5) while closing the opening (4), or in an open state where it is separated from the first flange (5) and placed in the inside space (1a) while opening the opening (4), and whose outside surface (6a) is configured to ensure a hermetically-sealed flattening onto itself of an outside surface (10a) of a second panel (10v) of a second complementary door (10) that is part of the second chamber (2),
• An interlocking means, configured to hold the first panel (6v) and the second panel (10v) when they are flattened against one another by their outside surfaces (6a and 10a),
• Movement actuation means (11b) configured to move the first panel (6v) between the closed and open states, and means for monitoring the movement actuation means (11b),
• wherein when the first panel (6v) is in the open state, the entrance/exit of the first chamber (1) being separated, an entrance/exit space (13a) in/of the inside space, in the general shape of a truncated cylinder, cone, or pyramid, that extends into the inside space at least approximately axially from the at least one opening (4) and the first flange (5), the entrance/exit space (13a) being part of a communication space between the two combined chambers making it possible to pass certain contents in to/out of the inside space, from one chamber to the other of the two chambers (1, 2), and
• An inside critical line (LCi) of contamination risk existing on the outside surface (6a) of the first panel (6v) in contact with the external environment and not overlapped by the outside surface (10a) of the second panel (10v), when the first and second panels (6v and 10v) are flattened against one another, wherein:
• The carrying means (11a) and the movement actuation means (11b) are arranged so that in the open state, the first panel (6v) is substantially separated beyond the boundary (13b, 13c) of the entrance/exit space (13a), an empty separation space (12) thus being made between the entrance/exit space (13a) and the first panel (6v) in the open state, beyond the lateral boundary (13c) and the distal end boundary (13b) of the entrance/exit space (13a) opposite the at least one opening (4) and the first flange (5), and
• The carrying means (11a) and the movement actuation means (11b), structurally integrated into the first door (6), constitute means for protection against the risks of contamination for the inside critical line (LCi), constituted by the separation space (12) of appropriate size formed and placed between the entrance/exit space (13a) and the inside critical annular line (LCi), so that the certain contents normally cannot reach the first panel (6v) during their passage into the entrance/exit space (13a).