Dialysis system including disposable cassette

A dialysis system comprising:

• a dialysis machine including a pump actuator, a valve actuator and a sorbent device;
• and
• a disposable cassette operable with the dialysis machine, the disposable cassette including
• (i) a housing including
• a dialyzer inlet port,
• a dialyzer outlet port,
• a pump portion configured to operate with the pump actuator,
• a valve portion configured to operate with the valve actuator,
• a venous port, and
• an arterial port,
• (ii) at least one dialyzer in fluid communication with the housing, the at least one dialyzer including
• a dialysate inlet, and
• a dialysate outlet;
• (iii) an arterial line for connecting to a patient, the arterial line connected to and extending externally from the arterial port of the housing;
• (iv) a venous line for connecting to the patient, the venous line connected to and extending externally from the venous port of the housing;
• (v) a first dialysate fluid connection connected to and extending from the dialyzer inlet port of the disposable cassette to the dialysate inlet of the at least one dialyzer, the first dialysate fluid connection in fluid communication with the sorbent device;
• and
• (vi) a second dialysate fluid connection connected to and extending from the dialyzer outlet port of the disposable cassette to the dialysate outlet of the at least one dialyzer, the second dialysate fluid connection in fluid communication with the sorbent device.

A dialysis system comprising:

• a dialysis machine including at least one pump actuator, at least one valve actuator, at least one sensor and a sorbent device;
• and
• a disposable pumping cassette operable with the dialysis machine, the disposable pumping cassette including
• at least one senor portion operable with the at least one sensor,
• at least one pumping portion operable with the at least one pump actuator, at least one valve portion operable with the at least one valve actuator,
• a first fluid connection in communication with a dialysate inlet of a dialyzer;
• and
• a second dialysate fluid connection in communication with a dialysate outlet of the dialyzer;
• and
• a recirculation line in fluid communication with the second dialysate fluid connection and the sorbent device.