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US 9,168,325 B2Granted
Hemostatic foam
AssigneesBaxter International Inc., Baxter Healthcare S.A.
InventorsAndreas Goessl, Katarzyna Gorna
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Abstract
The invention discloses a pharmaceutical hemostatic liquid foam base preparation comprising albumin as foaming agent and a fibrinogen precipitating substance and optionally a coagulation inducing agent, wherein albumin as foaming agent is present in native form; a method for the production of a transient hemostatic liquid foam; the transient hemostatic liquid foam; and a kit for making the foam.
Claims27
A method for preparing a transient pharmaceutical hemostatic liquid foam, the method comprising:
- providing a pharmaceutical hemostatic liquid foam base preparation comprising albumin and thrombin, wherein:
- albumin is present in its native form,
- albumin is not crosslinked, and
- thrombin is present in a concentration of 100 to 10000 IU/ml;
- and
- contacting the pharmaceutical hemostatic liquid foam base preparation with a foaming gas so as to obtain the transient pharmaceutical hemostatic liquid foam.
3 more elements
Dependencies are inferred from the claim text.