Growth hormone polypeptides and methods of making and using same
AssigneeAmunix Operating Inc.
InventorsVolker Schellenberger, Joshua Silverman, Willem P. Stemmer, Chia-wei Wang, Nathan Geething, Jeffrey L. Cleland, Benjamin Spink
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Abstract
The present invention relates to compositions comprising growth hormone linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of making and using such compositions in treatment of growth hormone-related diseases, disorders, and conditions.
Claims20
An isolated fusion protein, comprising the growth hormone (GH) sequence of SEQ ID NO:1 linked to an extended recombinant polypeptide (XTEN), wherein the fusion protein has at least 90% sequence identity to the sequence of SEQ ID NO:
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Dependencies are inferred from the claim text.