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US 9,168,254 B2Granted
Polymorphs of ARRY-380, a selective HER 2 inhibitor and pharmaceutical compositions containing them
AssigneeArray BioPharma Inc.
InventorsDonald T. Corson, Christopher M. Lindemann, Daniel J. Watson
Life of this patent
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Abstract
Polymorphs of N4-(4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)-3-methylphenyl)-N6-(4,4-dimethyl-4,5-dihydrooxazol-2-yl)quinazoline-4,6-diamine are provided herein. Processes for preparing the polymorphs and pharmaceutical composition comprising the polymorphs are also disclosed.
Claims127
A crystalline polymorph of N4-(4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)-3-methylphenyl)-N6-(4,4-dimethyl-4,5-dihydrooxazol-2-yl)quinazoline-4,6-diamine freebase.
Dependencies are inferred from the claim text.