Isolation of a dual COX-2 and 5-lipdxygenase inhibitor from Acacia
AssigneeUnigen, Inc.
InventorsQi Jia, Timothy C. Nichols, Eric E. Rhoden, Scott Waite
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Abstract
The present disclosure provides compositions and methods for alleviating inflammatory-associated diseases and conditions. These methods include administering individual and/or a mixture of multiple flavans isolated from a single or multiple Acacia genus of plants. The present disclosure also includes methods for isolating and purifying from an Acacia genus of plants a composition of flavans having dual specificity for cyclooxygenase (COX-2) and 5-lipoxygenase (5-LO) enzymes.
Claims8
A method for reducing joint discomfort, comprising administering to a human or non-human animal having joint discomfort a therapeutically effective amount of a composition comprising an Acacia extract enriched for flavans containing catechin and/or epicatechin, wherein the method alleviates cyclooxygenase and 5-lipoxygenase mediated inflammation in the human or non-human animal having joint discomfort.
Dependencies are inferred from the claim text.