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US 9,168,238 B2Granted
Levothyroxine formulations
AssigneeFresenius Kabi USA, LLC
InventorsJohn Zhiqiang Jiang, Arunya Usayapant, George Monen
Life of this patent
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Abstract
A levothyroxine composition includes levothyroxine sodium and mannitol. The composition is a lyophilized solid. The composition may include from 100 to 500 micrograms levothyroxine sodium and from 2 to 4 milligrams mannitol.
Claims30
A lyophilized solid composition, comprising:
- about 100 micrograms of levothyroxine sodium;
- a buffer;
- and
- between 2 and 4 milligrams of mannitol.
1 more element
A lyophilized solid composition, comprising:
- about 200 micrograms of levothyroxine sodium;
- a buffer;
- and
- between 2 and 4 milligrams of mannitol.
1 more element
A lyophilized solid composition, comprising:
- about 500 micrograms of levothyroxine sodium;
- a buffer;
- and
- between 2 and 4 milligrams of mannitol.
1 more element
Dependencies are inferred from the claim text.