Fibrous polymer scaffolds having diametrically patterned polymer fibers
AssigneeNanoNerve, Inc.
InventorsShyam Patel, Kyle Kurpinski
Life of this patent
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Abstract
Fibrous polymer scaffolds having at least one layer of diametrically patterned fibers, as well as methods of manufacture, are provided. The scaffolds can be formed of multiple layers and the extent and direction of alignment of each layer can be controlled. Fabrication systems and methods for producing such scaffolds including apparatuses and processes are also provided.
Claims14
A fibrous polymer scaffold, comprising a first layer and second layer of polymer fibers wherein the fibers of the first layer are diametrically patterned and the fibers of the second layer are randomly or uniaxially oriented.
A method of treating an injury or enhancing tissue growth in a subject, comprising:
- applying a fibrous polymer scaffold comprising a first layer of diametrically patterned polymer fibers such that:
- (i) the first layer contacts a defect in a tissue of the subject;
- and
- (ii) a convergence region of the first layer is placed in contact with the center of the defect.
A kit for the repair of wounds, surgical incisions or biopsies comprising:
- (i) a fibrous polymer scaffold comprising a first layer of diametrically patterned polymer fibers;
- and
- (ii) instructions for using the scaffold to repair wounds, surgical incisions or biopsies by promoting the regeneration of at least one anatomical biological component selected from abdominal wall, amniotic sac, bladder, blood vessels, brain, cardiac tissue, fascia, gingival tissue, intestine, ligaments, meningeal tissue, mucous membranes, muscle, nerves, skin, spinal cord, stomach and tendons.
Dependencies are inferred from the claim text.