System and method for tissue treatment using non-symmetric radio-frequency energy waveform
AssigneeInvasix Ltd.
InventorMichael Kreindel
Life of this patent
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Abstract
A method for soft tissue destruction comprises applying high voltage pulses causing irreversible electroporation alternating with low amplitude pulses of opposite polarity balanced to provide negligible average current and minimize risk of electrical shock. The method may be accompanied by tissue heating to reduce the electroporation threshold and negative pressure for skin shaping and optimal voltage distribution.
Claims22
A method of tissue destruction using non-symmetrical radio-frequency (NSRF) irreversible electroporation (IEP), the method comprising:
- coupling at least one electrode to tissue to be treated;
- and
- applying at least one cycle of alternating voltage to the tissue via the at least one electrode having at least first and second wave parts having opposite polarities and unequal amplitudes;
- wherein the first wave part amplitude is above an IEP threshold and the second wave part amplitude is below the IEP threshold.
A method of tissue destruction using non-symmetrical radio-frequency (NSRF) irreversible electroporation (IEP), the method comprising:
- coupling at least one electrode to tissue to be treated;
- and
- applying at least one cycle of alternating voltage to the tissue via the at least one electrode having at least first and second wave parts having opposite polarities and unequal amplitudes, the first wave part amplitude being above an IEP threshold and the second wave part amplitude being below the IEP threshold, and the first wave part duration being shorter than the second wave part duration such that the average current during the at least one cycle is approximately zero.
Dependencies are inferred from the claim text.