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US 9,164,100 B2Granted
Systems and methods for high-throughput detection of an analyte in a sample
AssigneeMagArray, Inc.
InventorsSebastian J. Osterfeld, Shan X. Wang
Life of this patent
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Abstract
Provided are high-throughput detection systems. The systems include a magnetic sensor device, a magnetic field source and a reservoir plate that includes a plurality of fluid reservoirs. The magnetic sensor device includes a support with two or more elongated regions each having a magnetic sensor array disposed at a distal end. Also provided are methods in which the subject high-throughput detection systems find use.
Claims9
A method for determining whether an analyte is present in a sample, the method comprising:
- (a) contacting a magnetic sensor device with a set of samples contained in a set of fluid reservoirs to generate a signal from the magnetic sensor device, the magnetic sensor device comprising a support with two or more elongated regions each having a magnetic sensor array comprising one or more magnetic sensor selected from the group consisting of a spin valve detector and a magnetic tunnel junction detect disposed at a distal end of the elongated region, wherein one or more magnetic sensor has an analyte-specific probe bound to a surface of the magnetic sensor;
- and
- (b) determining with a signal processing unit whether the analyte is present in each sample based on the signal from the magnetic sensor device, wherein the determining comprises receiving the signal from the magnetic sensor device and processing the signal to obtain a result of whether the analyte is present in each sample.
Dependencies are inferred from the claim text.