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US 9,151,763 B2Granted
Systems and methods for high-throughput detection of an analyte in a sample
AssigneeMagArray, Inc.
InventorsSebastian J. Osterfeld, Shan X. Wang
Life of this patent
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Abstract
Provided are high-throughput detection systems. The systems include a magnetic sensor device, a magnetic field source and a reservoir plate that includes a plurality of fluid reservoirs. The magnetic sensor device includes a support with two or more elongated regions each having a magnetic sensor array disposed at a distal end. Also provided are methods in which the subject high-throughput detection systems find use.
Claims19
A high-throughput detection system comprising:
- (a) a magnetic sensor device comprising a support with two or more elongated regions each having a magnetic sensor array comprising one or more magnetic sensor selected from the group consisting of a spin valve detector and a magnetic tunnel junction detector disposed at a distal end of the elongated region, wherein one or more magnetic sensor has an analyte-specific probe bound to a surface of the magnetic sensor;
- (b) a magnetic field source;
- and
- (c) a reservoir plate comprising sequential sets of a plurality of fluid reservoirs,
- wherein the system is configured to position the magnetic sensor arrays in the sequential sets of the fluid reservoirs.
2 more elements
A high-throughput detection system comprising:
- (a) a magnetic field source;
- (b) a first reservoir plate actuator configured to position a reservoir plate having sequential sets of a plurality of fluid reservoirs into an operative relationship with a magnetic sensor device;
- and
- (c) the magnetic sensor device, wherein the magnetic sensor device comprises a support with two or more elongated regions each having a magnetic sensor array comprising one or more magnetic sensor selected from the group consisting of a spin valve detector and a magnetic tunnel junction detector disposed at a distal end of the elongated regions, wherein one or more magnetic sensor has an analyte-specific probe bound to a surface of the magnetic sensor,
- wherein the system is configured to position the two or more magnetic sensor arrays in the sequential sets of the fluid reservoirs.
2 more elements
A magnetic sensor device comprising:
- a support with two or more elongated regions each having a magnetic sensor array comprising one or more magnetic sensor selected from the group consisting of a spin valve detector and a magnetic tunnel junction detector disposed at a distal end of the elongated region, wherein one or more magnetic sensor has an analyte-specific probe bound to a surface of the magnetic sensor.
Dependencies are inferred from the claim text.