Synthesis of fluorinated ethers
AssigneeHalocarbon Products Corporation
InventorsJoel Swinson, Barry Jones, Danny Graham, Neville Pavri
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Abstract
A process for preparing fluorinated ethers, such as desflurane, comprises reacting the corresponding chlorinated ether, such as isoflurane, with anhydrous hydrogen fluoride in the vapor phase in the presence of chromia catalyst. It is emphasized that this abstract is provided to comply with the rules requiring an abstract which will allow a searcher or other reader quickly to ascertain the subject matter of the technical disclosure. It is submitted with the understanding that it will not be used to interpret or limit the scope or meaning of the appended issued claims.
Claims16
A process for the preparation of 2-difluoromethoxy-1,1,1,2-tetrafluoroethane (desflurane) of the formula:
- CF3—CHF—O—CF2H
- which comprises reacting 2-chloro-2-difluoromethoxy-1,1,1-trifluoroethane (isoflurane) of the formula:
- CF3—CHCl—O—CF2H
- with anhydrous HF in the presence of a chromia catalyst.
Dependencies are inferred from the claim text.