Fluid purification system
AssigneesOregon State University, Outset Medical, Inc.
InventorsRichard B. Peterson, James R. Curtis
Life of this patent
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Abstract
Certain disclosed embodiments concern systems and methods of preparing dialysate for use in a home dialysis system that is compact and light-weight relative to existing systems and consumes relatively low amounts of energy. The method includes coupling a household water stream to a dialysis system; filtering the water stream; heating the water stream to at least about 138 degrees Celsius in a non-batch process to produce a heated water stream; maintaining the heated water stream at or above at least about 138 degrees Celsius for at least about two seconds; cooling the heated water stream to produce a cooled water stream; ultrafiltering the cooled water stream; and mixing dialysate components into the cooled water stream in a non-batch process.
Claims21
A fluid purification system having an inlet and an outlet, and defining a fluid flow pathway, comprising:
- a pump;
- a microfluidic pasteurizer downstream of the pump and coupled to the fluid flow pathway, the fluid flow pathway comprising
- (a) a first region where fluid flows in a first direction at a first temperature;
- (b) a heater region downstream of the first region, and including at least one heater that transfers heat into the fluid flowing through the heater region at the first temperature to increase the temperature to a second temperature greater than the first temperature to pasteurize the fluid flowing through the pathway;
- and
- (c) a second region downstream of the heater region where fluid flows in a second direction at a temperature greater than the first temperature, wherein fluid flowing in the second region thermally communicates with fluid flowing in the first region such that heat transfers from fluid flowing in the second region to fluid flowing in the first region resulting in a temperature reduction in the fluid as it flows through the second region, wherein fluid flows out of the pathway through the outlet at a temperature less than the second temperature;
- and
- a throttling valve downstream of the microfluidic pasteurizer, wherein the pump and the throttling valve operate in a closed loop control setup to maintain the fluid at a desired pressure and flow rate as the fluid passes through the pasteurizer.
A method for purifying a fluid, comprising:
- introducing a fluid stream into a fluid pathway;
- passing the fluid stream through a pump configured to achieve a predetermined fluid pressure in the fluid flow pathway;
- passing the fluid through a microfluidic pasteurizer coupled to the fluid flow pathway, the fluid flow pathway comprising
- (a) a first region where the fluid flows in a first direction at a first temperature;
- (b) a heater region downstream of the first region, and including at least one heater that transfers heat into the fluid flowing through the heater region at the first temperature to increase the temperature to a second temperature greater than the first temperature to pasteurize the fluid flowing through the pathway;
- and
- (c) a second region downstream of the heater region where fluid flows in a second direction at a temperature greater than the first temperature, wherein fluid flowing in the second region thermally communicates with fluid flowing in the first region such that heat transfers from fluid flowing in the second region to fluid flowing in the first region resulting in a temperature reduction in the fluid as it flows through the second region, wherein fluid flows out of the pathway at a temperature less than the second temperature;
- and
- passing the fluid stream through a throttling valve after the fluid exits the microfluidic pasteurizer, wherein the pump and the throttling valve operate in a closed-loop to collectively maintain the fluid at a flow rate and pressure that inhibits the fluid from undergoing a phase change in the pasteurizer.
Dependencies are inferred from the claim text.