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US 9,138,444 B2Granted
Dried collagenous biomaterial medical device
AssigneeCook Biotech Incorporated
InventorsMichael C. Hiles, Umesh H. Patel
Life of this patent
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Abstract
The invention involves a submucosa tissue that has the capability of being shape formed or shape configured. The submucosa involves a purified form of submucosa tissue. Optionally, the submucosa can be packaged in such a manner to permit sterility or maintain sterility of the submucosa.
Claims21
A collagenous biomaterial medical device, comprising:
- a sterile pouch containing a lyophilized multilaminate construct including multiple sheets of collagenous matrix tissue obtained as said sheets from a tissue source and retaining a native collagen biomaterial structure;
- said lyophilized multilaminate construct prepared by a process including lyophilizing said multiple sheets while in contact with one another;
- said collagenous matrix having a density greater than 0.10 grams per cubic centimeter and less than 0.65 grams per cubic centimeter;
- and
- said collagenous matrix containing at least one biotropic agent, wherein the biotropic agent is a proteoglycan, a glycosaminoglycan, or a growth factor.
2 more elements
A collagenous biomaterial medical device, comprising:
- a sterile pouch containing a lyophilized multilaminate construct including multiple sheets of collagenous matrix tissue obtained as said sheets from a tissue source and retaining a native collagen biomaterial structure;
- said lyophilized multilaminate construct prepared by a process including lyophilizing said multiple sheets while in contact with one another;
- said collagenous matrix having a density greater than 0.10 grams per cubic centimeter and less than 0.65 grams per cubic centimeter;
- and
- said collagenous matrix inducing angiogenic activity upon implantation into a mammal.
2 more elements
Dependencies are inferred from the claim text.