Biguanide derivative, preparation method thereof, and pharmaceutical composition containing same as an active ingredient

A compound of Formula 1 or a pharmaceutically acceptable salt thereof:

• wherein, R1 is a non-hydrogen substituent selected from the group consisting of C1-6 alkyl substituted with phenyl;
• C1-6 alkyl substituted with C5-12 heteroaryl wherein C5-12 heteroaryl is selected from the group consisting of furanyl, and pyridinyl;
• phenyl unsubstituted or substituted with halogen or C1-4 alkyl substituted with halogen, and unsubstituted C3-10 cycloalkyl;
• wherein the phenyl of C1-6 alkyl substituted with phenyl is unsubstituted or substituted with at least one non-hydrogen substituent selected from the group consisting of C1-4 alkoxy and halogen,
• R2 is unsubstituted C1-7 alkyl or hydrogen;
• and
• R3 is C1-6 alkyl substituted with phenyl or naphthyl;
• or the compound of Formula I is N4-methyl-N5,N5-(benzyl)(methyl) biguanide.