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US 9,132,231 B2Granted
Drug delivery device
AssigneeAlkermes Pharma Ireland Limited
InventorsJoseph Gross, Izrail Tsals, Gilad Lavi, Gil Yigal, Ehoud Carmel
Life of this patent
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Abstract
A drug delivery device having a housing containing a gas generator controlled by an electronic controller. The gas generator generates gas into a reciprocable chamber, whereby reciprocation of the chamber causes a lever to reciprocate a pawl, and this action causes a ratchet to undergo incremental advancement. The device may also be provided with manual control for delivering a bolus dose of drug when necessary.
Claims14
A wearable drug delivery device, comprising:
- a housing with an adherent patient surface for placing on a patient, and a reservoir disposed within the housing;
- a cannula in fluid communication with the reservoir and movable relative to the patient surface between a retracted position within the housing and an exposed position in which at least a portion of the cannula extends through the patient surface outside of the housing;
- a piston slidably supported within the reservoir and operable to expel a drug from the reservoir;
- a first drive member movably disposed within the housing and having a first portion;
- and
- a second drive member at least partially disposed within the reservoir and having a second portion that is slidingly engageable with the first portion of the first drive member;
- wherein the first and second drive members cooperate to slidably displace the piston in a first linear direction to expel a drug from the reservoir;
- and
- wherein the first drive member engages the second drive member to prevent the piston from moving in a second direction opposite to the first linear direction.
6 more elements
A method of manufacturing a wearable drug delivery device, comprising:
- providing a housing having a reservoir disposed therein, the reservoir having a piston slidably supported therein that is operable to expel a drug from the reservoir;
- providing an adherent patient surface on the housing for adhering the device to the patient;
- providing a movable a cannula in the housing, the cannula being movable from a retracted position within the housing to an exposed position in which at least a portion of the cannula extends through the patient surface outside of the housing;
- fluidly connecting the cannula to the reservoir;
- providing a first drive member to be displaceable within the housing, the first drive member having a first portion;
- providing a second drive member at least partially within the reservoir, the second drive member having a second portion that is slidingly engageable with the first portion of the first drive member;
- wherein providing the first and second drive members comprises:
- operatively connecting the first and second drive members to cooperate to slidably displace a piston in the reservoir in a first linear direction to expel a drug from the reservoir;
- and
- engaging the first drive member with the second drive member to prevent the piston from moving in a second linear direction opposite to the first linear direction.
7 more elements
Dependencies are inferred from the claim text.