US 9,132,177 B2 · Composition of tumor-associated peptides and related anti-cancer vaccine for the treatment of gastric cancer and other cancers

Abstract

The present invention relates to immunotherapeutic peptides and their use in immunotherapy, in particular the immunotherapy of cancer. The present invention discloses tumor-associated T-helper cell peptide epitopes, alone or in combination with other tumor-associated peptides that serve as active pharmaceutical ingredients of vaccine compositions which stimulate anti-tumor immune responses. In particular, the composition of the peptides of the present invention can be used in vaccine compositions for eliciting anti-tumor immune responses against gastric cancers (GC).

Claims10

Dependent claims

A pharmaceutical composition, comprising at least two peptides, wherein said at least two peptides are HLA-A*024 ligands consisting of an amino acid sequence according to SEQ ID NO:

1 and SEQ ID NO:
2, and wherein said peptides are in the form of a pharmaceutically acceptable salt.

Dependencies are inferred from the claim text.

Facts

Application

13/051,568Filed 18 Mar 2011 · us provisional application

Priority

GB 1004575.519 Mar 2010

Published

US 2011/0229524 A122 Sep 2011

Granted

15 Sep 2015

Term ends

Not estimatedThe source records don’t support an estimate.

Classification13 codes

C07K 14/4748
Not used: tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
A61K 39/0011
Vertebrate antigens: cancer antigens
A61P 1/00
Drugs for disorders of the alimentary tract or the digestive system
A61P 35/00
Antineoplastic agents

Composition of tumor-associated peptides and related anti-cancer vaccine for the treatment of gastric cancer and other cancers

Life of this patent

Composition of tumor-associated peptides and related anti-cancer vaccine for the treatment of gastric cancer and other cancers

Life of this patent

Abstract

Claims10