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US 9,127,276 B2Granted
Conjugated antisense compounds and their use
AssigneeIsis Pharmaceuticals, Inc.
InventorsThazha P. Prakash, Punit P. Seth, Eric E. Swayze
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Abstract
Provided herein are oligomeric compounds with conjugate groups. In certain embodiments, the oligomeric compounds are conjugated to N-Acetylgalactosamine.
Claims6
A compound having the formula (XXVI):
- wherein:
- T2 is a group comprising a nucleoside, a nucleotide, a monomeric subunit, a reactive ester, a linker, a cleavable moiety or an oligomeric compound.
Dependencies are inferred from the claim text.