Anti-cancer compositions and methods
AssigneeThe Penn State Research Foundation
InventorsGavin P. Robertson, Arati K. Sharma, Arun K. Sharma, Shantu G. Amin, Dhimant H. Desai
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AssigneeThe Penn State Research Foundation
InventorsGavin P. Robertson, Arati K. Sharma, Arun K. Sharma, Shantu G. Amin, Dhimant H. Desai
Estimating the term…
Anti-cancer compositions and methods are described including one or more isothiocyanates and/or isoselenocyanates. Methods of treating a subject are provided according to embodiments of the present invention which include administering a therapeutically effective amount of a composition including an isothiocyanate and/or isoselenocyanate to a subject having a condition characterized by Akt dysregulation. Administering a therapeutically effective amount of a composition including an isothiocyanate and/or isoselenocyanate to a subject detectably increases apoptosis and/or decreases proliferation of cancer cells, particularly cancer cells characterized by Akt dysregulation.
A method of modulating Akt dysregulation in a cell, comprising:
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