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US 9,123,099 B2Granted
Systems with workstations and circuits for generating images of global injury
AssigneeWake Forest University Health Sciences
InventorsWilliam Gregory Hundley, Craig A. Hamilton, Ralph B. D'Agostino
Life of this patent
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Abstract
Physician interactive workstations with global voxel distribution visualization may also include one or more of a 3-D color scale image of a population of voxel in target regions, organs or systems. The workstation may be configured to evaluate intensity or other measures of voxels of patient images associated with tissue for early detection of a global injury.
Claims19
A system, comprising:
- a circuit for generating and comparing 3-D images of cardiac tissue using x, y, z coordinates of voxels obtained from cardiac Magnetic Resonance (cMR) images of a patient and an associated measure of one or more voxel characteristic of a respective voxel and determining cell injury that is not visually detectable at a normal resolution of the cMR image slices;
- and
- a workstation with a display in communication with or including the circuit for presenting the generated images.
A system, comprising:
- a circuit for generating a 3-D image of cadiac tissue using x, y, z coordinates of voxels obtained from cardiac Magnetic Resonance (cMR) images of a patient and an associated measure of one or more voxel characteristics of a respective voxel;
- and
- a workstation with a display in communication with or including the circuit for presenting the generated image,
- wherein the circuit is configured to electronically distinguish cardiac injury associated with myocardial infarct from cardiac injury associated with cardiotoxicity.
1 more element
A system, comprising:
- a circuit for generating a 3-D image of cardiac tissue using x, y, z coordinates of voxels obtained from cardiac Magnetic Resonance (cMR) images of a patient and an associated measure of one or more voxel characteristics of a respective voxel;
- and
- a workstation with a display in communication with or including the circuit for presenting the generated image,
- wherein the circuit is configured to generate the 3-D image to illustrate a global injury, wherein the global injury is a change in tissue composition and/or function that is not visually detectable in the patient cMR images or that is in a substantially randomly distributed pattern in the target tissue, and
- wherein the circuit is configured to generate the 3-D image to illustrate a cardiotoxicity-induced global cardiac injury.
2 more elements
A system, comprising:
- a circuit for comparing MRI images of cardiac tissue using x, y, z coordinates of voxels obtained from first and second sets of a plurality of cardiac Magnetic Resonance (cMR) image slices of a patient obtained at different points in time and an associated measure of one or more defined voxel characteristic of a respective voxel, and determining cell injury that is not visually detectable at a normal resolution of the cMR image slices;
- and
- a workstation with a display in communication with or including the circuit for presenting the images.
Dependencies are inferred from the claim text.