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US 9,119,898 B2Granted
Medical implant including a 3D mesh of oxidized cellulose and a collagen sponge
AssigneeSofradim Production
InventorsYves Bayon, Sébastien Ladet, Olivier Lefranc, Philippe Gravagna
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Abstract
The present invention relates to A bioresorbable implant comprising: a bioresorbable porous layer including a biopolymer foam and defining first pores, a bioresorbable porous three-dimensional mesh made from a microbial cellulose and defining second pores, wherein the bioresorbable porous layer is disposed in the bioresorbable porous three-dimensional mesh. The invention also relates to a method of making a bioresorbable implant.
Claims17
A bioresorbable implant comprising:
- a bioresorbable porous layer including a biopolymer foam defining first pores, and a three-dimensional density from about 30 mg collagen/cm3 to about 150 mg collagen cm3,
- a bioresorbable porous three-dimensional mesh made from a microbial cellulose having a thickness of about 0.1 cm to about 3 cm, and defining second pores from about 0.5 mm to about 5 mm, wherein the bioresorbable porous layer is disposed in the bioresorbable porous three-dimensional mesh, and
- a non-porous film applied to the bioresorbable porous three-dimensional mesh including the bioresorbable porous layer.
A method of making a bioresorbable implant, comprising:
- adding an aqueous acid solution or suspension of collagen to a bioresorbable porous three-dimensional mesh made from a microbial cellulose having a thickness of about 0.1 cm to about 3 cm, and defining second pores from about 0.5 mm to about 5 mm,
- lyophilizing the solution to create a bioresorbable foam layer in the bioresorbable porous three-dimensional mesh, wherein the bioresorbable foam layer includes a three-dimensional density from about 30 mg collagen/cm3 to about 150 mg collagen/cm3, and
- applying a non porous layer to the bioresorbable porous three-dimensional mesh that has been filled with the bioresorbable foam layer.
Dependencies are inferred from the claim text.