Recombinant HVT vectors expressing antigens of avian pathogens and uses thereof
AssigneeMerial Limited
InventorsMichel Bublot, Teshome Mebatsion, Joyce Pritchard, Perry Linz
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Abstract
The present invention provides recombinant herpesvirus of turkeys (HVT) vectors that contain and express antigens of avian pathogens, compositions comprising the recombinant HVT vectors, polyvalent vaccines comprising the recombinant HVT vectors and one or more wild type viruses or recombinant vectors. The present invention further provides methods of vaccination against a variety of avian pathogens and method of producing the recombinant HVT vectors.
Claims21
A composition or vaccine comprising one recombinant herpesvirus of turkeys (HVT) vector comprising at least one or more heterologous polynucleotides coding for and expressing at least one antigen of an avian pathogen, wherein the polynucleotide encodes a Newcastle Disease Virus F (NDV-F) polypeptide and is operably linked to an SV40 promoter, and wherein the polynucleotide is codon-optimized.
Dependencies are inferred from the claim text.