Pressure-regulating vial adaptors

A medical adaptor capable of coupling with a sealed container, the medical adaptor having a filter chamber surrounding at least a portion of a regulator assembly channel, the medical adaptor comprising:

• a housing comprising:
• a medical connector interface;
• an access channel capable of removing medicinal fluid extending between the medical connector interface and a distal access port;
• and
• a regulator channel comprising a distal regulator passageway, a regulator valve, and a proximal regulator passageway;
• and
• a regulator assembly comprising:
• a regulator interface defining a regulator assembly channel and capable of fluid communication with the proximal regulator passageway;
• a storage chamber having a storage height and a storage depth and a storage volume;
• a filter chamber in fluid communication with an ambient environment, wherein the filter chamber has an inner diameter at least partially defined by an inner wall, and an outer diameter at least partially defined by an outer wall, and wherein the filter chamber surrounds at least a portion of the regulator assembly channel;
• a flexible enclosure capable of fluid communication with the proximal regulator passageway, the flexible enclosure capable of transitioning between a contracted configuration and an expanded configuration;
• an intake valve in fluid communication with the flexible enclosure and the proximal regulator passageway when the regulator interface is connected to the proximal regulator aperture, the intake valve capable of transitioning between an opened configuration and a closed configuration, the intake valve comprising an elastomeric member having an inner orifice, the inner orifice defining at least a portion of a fluid path between the flexible enclosure and the proximal regulator passageway when the intake valve is in the closed configuration, wherein the intake valve facilitates fluid communication between an interior of the regulator assembly and the filter chamber when the intake valve is in the opened configuration;
• and
• a filter positioned within the filter chamber and filling a space defined between the inner diameter of the filter chamber and the outer diameter of the filter chamber.