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US 9,078,867 B2Granted
Vaccine against beta-herpesvirus infection and use thereof
OwnerChristian Thirion, Ulrich Koszinowski +2inventors
InventorsChristian Thirion, Ulrich Koszinowski, Christian A. Mohr, Zsolt Ruzsics
Life of this patent
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Abstract
The present invention is related to a beta-herpesvirus, wherein the beta-herpesvirus is spread-deficient.
Claims9
A recombinant human cytomegalovirus (HCMV), wherein said virus comprises a deletion of nucleotides 122631-123667 and 181653-189191 of SEQ ID NO:
- 20, and wherein SEQ ID NO:
- 34 is inserted into said virus to replace deleted nucleotides 12263-123667 from SEQ ID NO:
- 20.
A recombinant HCMV, wherein said virus comprises a deletion of nucleotides 58443-59622, 181653-189191 of SEQ ID NO:
- 20, and wherein SEQ ID NO:
- 32 is inserted into said virus to replace deleted nucleotides 58443-59622 from SEQ ID NO:
- 20.
A recombinant HCMV, wherein said virus comprises a deletion of nucleotides 62130-63260 and 181653-189191 of SEQ ID NO:
- 20, and wherein SEQ ID NO:
- 33 is inserted into said virus to replace deleted nucleotides 62130-63260 from SEQ ID NO:
- 20.
Dependencies are inferred from the claim text.