Microscopy imaging

An apparatus comprising:

• a portable housing comprising:
• an imaging integrated circuit comprising
• a two-dimensional array of pixels at a photosensitive surface to capture a two-dimensional image of a specimen, the width of the pixels along each of the two dimensions of the array being 5 microns or smaller, the array having at least 1 million pixels,
• the surface to receive at least a part of a specimen at a distance from the surface equivalent to less than about half of an average size of the pixels,
• the pixels situated within the array to generate signals that capture a two-dimensional image of the specimen that extends along each of the two dimensions of the array,
• a chamber for the specimen, the chamber being defined partly by a chamber lid comprising a top, spaced apart from the surface by a distance less than 1 millimeter, to transmit light to illuminate the specimen,
• the chamber lid being movable to permit a liquid specimen to be applied to the surface, or the chamber lid comprising a fluid channel to carry a fluid specimen into the chamber and in contact with the surface, or both,
• the specimen to be held statically after being applied to the surface or carried into the chamber, or the two-dimensional image being captured at once as the fluid specimen flows past the surface,
• electronics comprising a circuit board coupled to the imaging integrated circuit, and
• a computing device to analyze information representing, or to display, the two-dimensional image of the specimen captured by the array, or both.