Coating formulations for scoring or cutting balloon catheters
AssigneeAngioScore, Inc.
InventorsUlrich Speck, Madeleine Caroline Berg
Life of this patent
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Abstract
The present invention is related to scoring or cutting balloon catheters carrying at least on a portion of their surface at least one oxidation-insensitive drug or oxidation-insensitive polymer-free drug preparation and at least one lipophilic antioxidant at a ratio of 3-100% by weight of the at least one lipophilic antioxidant in relation to 100% by weight of the drug, wherein the at least one oxidation-insensitive drug is selected of taxanes, thalidomide, statins, corticoids and lipophilic derivatives of corticoids, and the at least one lipophilic antioxidant is selected of nordihydroguaiaretic acid, resveratrol and propyl gallate.
Claims12
A scoring or cutting angioplasty balloon catheter carrying at least on a portion of its surface a therapeutically effective amount of the oxidation-insensitive drug paclitaxel and an amount of the lipophilic antioxidant propyl gallate that will protect the paclitaxel from premature loss during delivery to an angioplasty site and that is 3-100% by weight of the paclitaxel;
- and an amount of polymer that is 0-20% by weight of the paclitaxel.
Dependencies are inferred from the claim text.