Compositions and methods for treating bone defects
AssigneeUniversity of Louisville Research Foundation, Inc.
InventorsMichael J. Voor, Robert L. Burden, Jr.
Life of this patent
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Abstract
A bone graft composition includes a biologically-resorbable cement and a plurality of processed bone particles, where each of the bone particles have a shape configured to interconnect with adjacent bone particles. A method for treating a bone defect using the bone graft compositions includes providing the bone graft composition and administering an effective amount of the bone graft composition to a site of a bone defect in a subject. Kits including a biologically-resorbable cement powder and a plurality of processed bone particles are also provided.
Claims24
A bone graft composition, comprising:
- a biologically-resorbable cement;
- and
- a plurality of processed bone particles, each of the bone particles being cut from an intact whole bone or a portion thereof, and each of the bone particles being dumbbell-shaped, having an elongated center portion and two enlarged end portions,
- wherein the plurality of processed bone particles comprise about 5 percent to about 50 percent by volume of the bone graft composition.
A kit, comprising:
- a biologically-resorbable cement powder;
- and
- a plurality of processed bone particles, each of the bone particles being cut from an intact whole bone or a portion thereof, and each of the bone particles being dumbbell-shaped, having an elongated center portion and two enlarged end portions,
- wherein the biologically-resorbable cement powder and the bone particles are included in the kit in amounts such that, when the biologically-resorbable cement powder and the bone particles are combined, the bone particles comprise about 5 percent to about 50 percent by volume of a resulting bone graft composition.
A bone graft composition, comprising:
- a biologically-resorbable cement;
- and
- a plurality of processed bone particles, each of the bone particles being dumbbell-shaped, having an elongated center portion and two enlarged end portions, and each of the bone particles being cut from an intact whole bone or a portion thereof.
Dependencies are inferred from the claim text.