Method to generate antibodies to ion channels
AssigneeUCB Pharma S.A.
InventorTerence Seward Baker
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Abstract
The present invention provides a method for generating a functionally modifying antibody to an ion channel comprising immunizing a host with a cyclic peptide comprising at least part of an extracellular sequence of said ion channel.
Claims19
A method for generating an antibody to a potassium ion channel having a function in the modulation of pain comprising immunizing a host with a cyclic peptide comprising at least part of an extracellular sequence of said ion channel, wherein the extracellular sequence of said ion channel is an E1 extracellular region or E3 extracellular region, and the cyclic peptide comprises between 5 and 30 amino acids from said extracellular region.
Dependencies are inferred from the claim text.