Peptides derivatized with A-B-C-D- and their therapeutical use

A peptide derivative comprising a peptide wherein at least one amino acid residue is derivatized with A-B-C-D-

• wherein (i) A- is
• wherein R is lower linear or branched alkyl, p is selected from the group consisting of 10, 11, 12, 13 and 14, and d is selected from the group consisting of 0, 1, 2, 3, 4 and 5, and
• B- is selected from the group consisting of
• wherein x is selected from the group consisting of 0, 1, 2, 3 and 4, and y is selected from the group consisting of 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11 and 12,
• or (ii) A is
• wherein n is selected from the group consisting of 14, 15, 16 17, 18 and 19, and B is selected from the group consisting of
• wherein x is selected from the group consisting of 0, 1, 2, 3 and 4, and together with either (i) or (ii)
• -C- is selected from the group consisting of
• wherein b and e are each independently selected from the group consisting of 0, 1 and 2, and c and f are each independently selected from the group consisting of 0, 1 and 2 with the proviso that b is 1 or 2 when c is 0, or b is 0 when c is 1 or 2, and e is 1 or 2 when f is 0, or e is 0 when f is 1 or 2, and
• -D- is attached to said amino acid residue and is a linker, represents a bond, or is absent.