Anticancer agents comprising peptides with cancer-specific toxicity
AssigneesKorea Advanced Institute of Science and Technology, Intelligent Synthetic Biology Center
InventorsSun Chang Kim, Su A Jang, Da Jung Kim, Bong Hyun Sung, Ki Jeong Lim, Ju Ri Shin, Young Woong Lee
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Abstract
The present invention relates a prophylactic or therapeutic composition for cancer, and more particularly, to a prophylactic or therapeutic composition for cancer comprising a peptide which is represented by an amino acid sequence of the following Formula (I), a method for preventing or treating cancer comprising the step of administering the peptide to a subject, and use of the peptide in the preparation of the prophylactic or therapeutic composition for cancer. (I) APKAMX1LLX2X3L-LX4LQKKGI wherein X1, X2, X3 and X4 are each independently R or K.
Claims3
A method for treating a cancer cell line in vitro, comprising the step of treating a cancer cell line with a peptide which is represented by SEQ ID NO. 1 or SEQ ID NO. 2, wherein the cancer cell line is a skin cancer, cervical cancer, lung cancer, rectal cancer, prostate cancer, or hematologic malignancies cell line.
Dependencies are inferred from the claim text.