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US 9,067,967 B2Granted
Peptides useful in the treatment and care of the skin and mucous membranes and their use in cosmetic or pharmaceutical compositions
AssigneeLipotec, S.A.
InventorsJosé María García Antón, Nuria Almiñana Domenech, Antonio Vicente Ferrer Montiel
Life of this patent
Estimating the term…
Abstract
Peptides of general formula (I), their stereoisomers, mixtures thereof and/or their cosmetically or pharmaceutically acceptable salts, a preparation process, cosmetic or pharmaceutical compositions which contain them and their use for the treatment and/or care of conditions, disorders and/or diseases of the skin and/or mucous membranes. R1—Wn—Xm-AA1-AA2-AA3-AA4-AA5-AA6-Yp—Zq—R2 (I)
Claims21
A peptide of general formula (I)
- R1—Wn—Xm-AA1-AA2-AA3-AA4-AA5-AA6-Yp—Zq—R2 (I)
- its stereoisomers, mixtures thereof and/or its cosmetic or pharmaceutical acceptable salts, wherein:
- AA1 is selected from the group consisting of -Ser-, -Thr- and -Tyr-;
- AA2 is selected from the group consisting of -Pro- and -Val-;
- AA3 is -Ala-;
- AA4 is selected from the group consisting of -Glu-, -Gly- and -Val-;
- AA5 is -Gly-;
- AA6 is selected from the group consisting of -Gln-, -Gly-, -His- and -Pro-;
- W, X, Y, Z are amino acids and are independently selected from amongst themselves;
- n, m, p and q are independently selected from amongst themselves and have a value of 0 or 1;
- n+m+p+q is lower than or equal to 2;
- R1 is selected from the group consisting of H, substituted or unsubstituted non-cyclic aliphatic group, substituted or unsubstituted alicyclyl, substituted or unsubstituted heterocyclyl, substituted or unsubstituted heteroarylalkyl, substituted or unsubstituted aryl, substituted or unsubstituted aralkyl and R5—CO—, wherein R5 is selected from the group consisting of H, substituted or unsubstituted non-cyclic aliphatic group, substituted or unsubstituted alicyclyl, substituted or unsubstituted aryl, substituted or unsubstituted aralkyl, substituted or unsubstituted heterocyclyl, and substituted or unsubstituted heteroarylalkyl;
- R2 is selected from the group consisting of —NR3R4, —OR3 and —SR3, wherein R3 and R4 are independently selected from the group consisting of H, substituted or unsubstituted non-cyclic aliphatic group, substituted or unsubstituted alicyclyl, substituted or unsubstituted heterocyclyl, substituted or unsubstituted heteroarylalkyl, substituted or unsubstituted aryl, and substituted or unsubstituted aralkyl;
- and
- with the condition that R1 and R2 are not α-amino acids.
12 more elements
Dependencies are inferred from the claim text.