Method for low-voltage termination of cardiac arrhythmias by effectively unpinning anatomical reentries
AssigneeWashington University
InventorsIgor R. Efimov, Valentin I. Krinski, Vladmir P. Nikolski
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AssigneeWashington University
InventorsIgor R. Efimov, Valentin I. Krinski, Vladmir P. Nikolski
Estimating the term…
A method for extinguishing a cardiac arrhythmia utilizes destructive interference of the passing of the reentry wave tip of an anatomical reentry through a depolarized region created by a relatively low voltage electric field in such a way as to effectively unpin the anatomical reentry. Preferably, the relatively low voltage electric field is defined by at least one unpinning shock(s) that are lower than an expected lower limit of vulnerability as established, for example, by a defibrillation threshold test. By understanding the physics of the electric field distribution between cardiac cells, the method permits the delivery of an electric field sufficient to unpin the core of the anatomical reentry, whether the precise or estimated location of the reentry is known or unknown and without the risk of inducting ventricular fibrillation. A number of embodiments for performing the method are disclosed.
An implantable system for treating ventricular tachyarrhythmias, the implantable system comprising:
A method for treating ventricular tachyarrhythmias in a patient, comprising:
A method for controlling an implantable therapy generator adapted to be implanted in a patient and operably connected to a plurality of implantable electrodes, the method comprising configuring the implantable therapy generator to:
Dependencies are inferred from the claim text.