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US 9,067,032 B2Granted
Method for treatment of lung infections by administration of aminoglycosides by aerolisation
AssigneeXellia Pharmaceuticals Aps
InventorThomas Norling
Life of this patent
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Abstract
The present invention regards a novel administration form and a novel administration regime useful in the treatment and prevention of a bacterial lung infection in patient in need thereof, in particular by providing a composition useful for aerosolization of a highly concentrated solution of aminoglycosides such as Tobramycin.
Claims18
A method for preventing or treating bacterial infections in the pulmonary system of a patient in need thereof comprising
- administering by inhalation an aerosolized dose of an aqueous solution of 150-250 mg/ml of an aminoglycoside antibiotic,
- wherein administering is with a metered dose inhalation device that provides an aerosol having a mass median aerodynamic diameter of 4-7 micrometer,
- wherein the metered dose inhaler has a spray nozzle unit providing said aerosols by transferring the composition through orifices.
Dependencies are inferred from the claim text.