Demineralized cancellous strip DBM graft
AssigneeWarsaw Orthopedic, Inc.
InventorNelson L. Scarborough
Life of this patent
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Abstract
An osteoimplant includes at least partially demineralized cancellous bone as a substrate, which is impregnated with demineralized cortical bone matrix (DBM). The implant may include a binding agent to adhere the DBM to the cancellous bone substrate, and may also include a soft tissue barrier that covers a portion of the external surface of the implant. The cancellous bone substrate may be selectively demineralized, so as to provide regions with greater malleability, and other regions with greater structural properties.
Claims21
An implant comprising a cancellous bone substrate and a demineralized cortical bone matrix (DBM) having a weight to weight ratio from 4 to 2, wherein the cancellous bone substrate has a porous matrix of interconnected pores, wherein the cancellous bone substrate is at least partially demineralized, wherein the DBM is in the form of particles having an average particle size between 50 μm and 900 μm and the average particle size of the DBM is less than an average pore size of the cancellous bone, wherein the porous matrix is impregnated with the demineralized cortical bone matrix (DBM) and the demineralized cortical bone matrix is embedded within the interconnected pores of the demineralized cancellous bone substrate, and wherein the embedded DBM particles are bound to the cancellous bone substrate, and a soft tissue barrier comprising a bone wax covering at least a portion of an external surface of the implant.
An implant comprising:
- a cancellous bone substrate;
- and a demineralized cortical bone matrix (DBM) having a weight to weight ratio of 4 to 2 and having a particle size of 50 μm to 250 μm;
- and
- a soft tissue barrier comprising a bone wax covering at least a portion of the external surface of the implant,
- wherein the cancellous bone substrate has a porous matrix of interconnected pores and wherein the cancellous bone substrate is at least partially demineralized, wherein the average particle size of the DBM is less than an average pore size of the cancellous bone, wherein the porous matrix is impregnated with the demineralized cortical bone matrix (DBM) and the demineralized cortical bone matrix is embedded within the interconnected pores to the at least partially demineralized cancellous bone substrate, and wherein the embedded DBM particles are bound to the cancellous bone substrate.
Dependencies are inferred from the claim text.