Ceramic biocomposite for bone regeneration
AssigneeUniversidad Autonoma De Occidente
InventorsSandra Arce Guerpero, Carlos Humberto Valencia
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Abstract
The invention relates to a ceramic biocomposite for bone regeneration, having a pH range of between 6.5 and 8.5, with an initial plasticity that allows the biocomposite to be easily moulded in situ and to set after 7 minutes, meaning that it can remain at the indicated location during the healing process. In addition, the biocomposite has demonstrated an ability to stimulate bone formation in hard-to-heal wounds. The material can act alone or in combination with other types of bone graft such as autografts, homografts or xenografts which act as a vehicle, as a binding material for endosseous prostheses or as a covering for endosseous implants or prostheses.
Claims4
A ceramic biocomposite for bone regeneration with a hardening time of from 7 to 15 minutes, which stimulates formation and increase of bone volume, comprising:
- a) a solid phase comprising:
- i. between 93% and 96% of tricalcium β-phosphate in relation to the weight of the total solid phase;
- ii. between 2.5% and 4% of calcium oxide in relation to the total weight of the solid phase;
- and
- iii. between 1.5% and 3.5% of zinc oxide in relation to the total weight of the solid phase;
- and
- b) a liquid phase comprising chitosan;
- wherein the solid phase to liquid phase ratio is about 0.67 thereby stimulating formation and increase of bone volume.
Dependencies are inferred from the claim text.