Method of using a probiotic microorganism for the treatment of diarrhea
AssigneeCedars-Sinai Medical Center
InventorsMark Pimentel, Henry C. Lin
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Abstract
Disclosed is a method of manipulating the rate of gastrointestinal transit in a mammalian subject. Also disclosed is the use, in the manufacture of a medicament for the treatment of constipation, of a selective inhibitor of methanogensis, a methanogen-displacing probiotic agent, or a prebiotic agent that inhibits the growth of methanogenic bacteria or promotes the growth of competing non-methanogenic intestinal flora. Alternatively, in accordance with the invention, is disclosed the use in the manufacture of a medicament for the treatment of diarrhea, of methane or a methane precursor, a methanogenic or other methane-enhancing probiotic agent, or a methanogenesis-enhancing prebiotic agent.
Claims8
A method of treating diarrhea in a subject in need thereof, comprising:
- providing a methane-enhancing probiotic microorganism selected from the group consisting of Methanobrevibacter smithii, Bacteroides spp., Clostridium butyricum, and combinations thereof;
- and
- administering the methane-enhancing probiotic microorganism to the subject to slow intestinal transit to treat the diarrhea.
A method of treating diarrhea in a subject in need thereof, comprising:
- providing a composition comprising a methane-enhancing probiotic microorganism selected from the group consisting of Methanobrevibacter smithii, Bacteroides spp., Clostridium butyricum, and combinations thereof and a carrier;
- and
- administering the composition to the subject to slow intestinal transit to treat the diarrhea.
Dependencies are inferred from the claim text.